Basic information: The project will support the growth of internationalization and the quality of the research environment in the Czech Republic and the development of researchers. The project will help determine the relationship between genes related to local adaptation, define their effect on climate change resistance, and model the distribution of gene variability. Project research will assess whether its relationship to environmental variation is explained solely by climatic differences between the areas in which individual gene variants occur, or by different climatic tolerances associated with these variants. In particular, the covariation of genes and BMR will be defined. Furthermore, there will be investigated the origin of gene/BMR variability in different glacial refugia, their role in spatial/ecological segregation, and their influence on the geographic distribution of intraspecific populations under different climate change scenarios using ENM approaches. In this way, there will be developed analytical tools that will make it possible to predict the resistance of species to global changes with great accuracy.

It is co-financed by the European Union

Rgistration No: CZ.02.01.01/00/22_010/0008118

Project duration: 1. 10. 2023 - 30. 09. 2025 

Investigator: Mgr. Marco Sánchez Escalante Ph.D. Institute of Animal Physiology and Genetics CAS, v. v. i.

MORE +

Basic information: The objectives of the project Centre of Excellence in Regenerative Medicine are as follows: 1) Implementation of planned research projects by implementing 6 research work packages in the field of regeneration and tissue engineering. WP1 will develop new and effective treatment options for CNS injuries based on the principles of regenerative medicine. WP2 will contribute to the development of a new and effective treatment option for neurodegeneration using unique chemical derivatives and nanomaterials. WP3 will elaborate methodologies crucial for cell and gene therapy of retinal degenerative diseases. WP4 focuses on the development of small diameter vascular grafts and vascular patches using tissue engineering methods. WP5 aims at the development of treatment of osteochondral defects. The aim of WP6 is the development of novel materials to promote healing of chronic wounds based on natural and synthetic polymers. 2) Creation/development of an excellent research team through the permanent involvement of 31 high quality key workers, including the long-term involvement of 17 other senior researchers, 13 technicians, 21 expert workers and students from abroad and other expert junior researchers and students. 3) Establishment of a minimum of seven new international collaborations and expansion of the existing ones. 4) Strengthening internationalisation by involving at least 21 foreign workers in work package research teams. The establishment of new and expansion of existing international collaborations will lead to the submission of at least 34 international grants and publication of at least 36 publications with foreign co-authorship. 5) Acquisition of instrumentation and infrastructure necessary for the implementation of research projects.

It is co-financed by the European Union

Rgistration No: CZ.02.01.01/00/22_008/0004562

Project duration: 1. 10. 2023 - 30. 06. 2028

Investigator: Insitute of Experimental Medicine, CAS

Other solver: University Hospital Hradec Králové, Institute of Physiology CAS, Institute of Chemical Proccess   CAS, Institute of Macromolecular Chemistry CAS, Institute of Animal Physiology and Genetics CAS, Faculty of Science, humanities and Education TUL, J.E. Purkyně University Ústí nad Labem Faculty of Science, Palacký university Olomouc Faculty of Science, Faculty of Chemical Technology UCT Prague, Brno University of Technology CEITEC

MORE +