MZE

MZE

Innovation of advanced bovine reproductive biotechnology to increase genetic gain in the population

Basic information: The main goal can be divided into sub-aims: Sub-aim 1 - Optimization of procedures i) isolation of selected BSP proteins from bovine seminal plasma; ii) recombinant production of BSP proteins; iii) testing the specificity of interactions of selected BSP proteins with spermatozoa. Sub-aim 2 - i) Testing the effect of media modifications on sperm quality parameters after sexing and cryopreservation ii) analysing the effect of specific protein concentration in media on IVF results of oocytes obtained post-mortem or OPU. Sub-aim 3 - Analysis of modified sperm sexation conditions on i) embryo implantation after artificial insemination; ii) embryo transfer success. Sub-aim 4 - i) Setting up a methodology for blastomere biopsy; ii) setup and optimization of genomic testing of embryos.

Registration No: QL26010328

Project Duration: 1.1. 2026 – 31.12.2030

Principal investigator:  doc. Ing. Luděk Stádník Ph.D. Czech University of Life Sciences Prague

Other solver:  Ing. Ondřej Šimoník, Ph.D. Institute of Biotechnology of the Czech Academy of Sciences

Other solver: doc. Dr. Ing. Josef Kučera Českomoravská společnost chovatelů, a.s.

Other solver: doc. Dr. Ing. Jiří Šichtař, Ph.D. EmbryoLab s.r.o.

Other solver: Ing. Veronika Kinterová, Ph.D. Institute of Animal Physiology and Genetics CAS, v. v. i.

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New methods of suppressing microbial infections in bees: Development of a new generation host-targeted synbiotic from pro-immune active bifidobacteria and lactobacilli

Basic information: The project aims to develop and validate a next-generation synbiotic for honey bees, composed of 4–8 selected strains of bifidobacteria and lactobacilli with pro-immunity and pro-metabolic effects. Strains will be chosen for their ability to ferment nectar- and pollen-derived carbohydrates and produce bioactive metabolites. The formulation will include a prebiotic component serving also as a cryo- and lyoprotectant. The synbiotic will be tested under lab and field conditions. The project covers production planning and market preparation. Results will be shared through workshops and lectures for beekeepers and students.

Registration No: QL26010035

Project Duration: 1.1. 2026 – 31.12.2030

Principal investigator:  doc. Ing. Jaroslav Havlík, Ph.D. Czech University of Life Sciences Prague

Other solver:  doc. Ing. Jiří Killer, Ph.D. Institute of Animal Physiology and Genetics CAS, v. v. i.

Other solver: MVDr. Martin Kamler Výzkumný ústav včelařský, s.r.o.

Other solver: doc. RNDr. Pavel Hyršl, Ph.D. Masaryk University Faculty of Science

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