Date of birth: 26th February 1988
Education
5th October 2015 | Ph.D. in Biochemistry: Centre for Interdisciplinary Research, D. Y. Patil University, Kolhapur-416006, Maharashtra, India. Title of thesis: "Synthesis and Characterization of Bovine Serum Albumin Nanoparticles and their Conjugates with Dextran for Wound Healing Potential". |
2011 | MSc. in Biochemistry: New arts commerce and science college, Ahmednagar, Savitribai Phule Pune University, Pune-411007, Maharashtra, India. (Specialization- Biochemistry). |
2008 | BSc. in Chemistry: Pemraj Sarda college, Ahmednagar, Savitribai Phule Pune University, Pune-411007, Maharashtra, India. (Specialization- Chemistry). |
Major scientific interests
- Polymer based nanoparticles particularly proteins, are becoming excellent candidates for retinal gene/bioactive molecules delivery. These nanoparticles are highly and indefatigably expressed throughout the retina are well-tolerated, safe and hold great potential for the treatment of RPE-associated diseases.
- The incorporation of bioactive molecule engineering strategies designed to improve phenotypic rescue in rod and cone photoreceptors and in RPE cells.
- The ability to target nanoparticles to different cell types and/or regions of the cell make them customizable for diverse applications especially in the retinal disease. We are focusing on the progress and future of polymeric nanoparticles; what will be required to make them appropriate retinal pharmaceutics.
Professional experience
10/2015-05/2016 | Working as Senior Research Fellow on DBT sanctioned project entitled "Delivery of drugs and cells to the cornea using silk protein-A novel therapeutic approach (DUK)" at Indian Institute of Technology, Kharagpur, West Bengal-721302, India |
07/2011-10/2015 | Ph. D. Thesis entitled "Synthesis and Characterization of Bovine Serum Albumin Nanoparticles and their Conjugates with Dextran for Wound Healing Potential" under the supervision of Prof. (Dr.) S.H. Pawar, Center for Interdisciplinary Research, D. Y. Patil University, Kolhapur-416006, India |
2009-2010 | Successfully completed the project entitled "Isolation and analysis of cereal, tuber and plant starch" for the partial fulfillment of M.Sc. degree in Biochemistry under the supervision of Prof. M. V. Padul, Department of Biochemistry, University of Pune, Pune-411007 |
Teaching experience
2012-2015 | Working as a Teaching assistant for research for M. Sc. Stem cells and Regenerative Medicine and M. Sc. Medical Physics, Centre for Interdisciplinary Research, D. Y. Patil University, Kolhapur-416006, India |
Fellowships, prizes
- Award of DBT- Senior Research Fellow, project entitled, "Delivery of drugs and cells to the cornea using silk protein-A novel therapeutic approach (DUK)" at Indian Institute of Technology, Kharagpur, West Bengal-721302, India.
- Best oral presentation in National Conference on "Recent Trends in Interdisciplinary Research in Material Science 2014" at Annasaheb Dange College of Engineering & Technology, Ashta, Sangali, Maharashtra, India.
- Best oral presentation in National Conference on "Biostatistics and Its Application in Research 2010" at Jijamata college of science and arts Bhenda, Newasa, Ahmednagar, Maharashtra, India.
Academic achievements
Total number of Research articles: 09
Total number of citations: 47
‘h’ Index: 05
i10 index: 01
Source
Publications
2016 | A. V. Raut, R. K. Satvekar, S. S. Rohiwal, A. P. Tiwari, A. Gnanamani, S. Pushpavanam, S. G. Nanaware & S. H. Pawar, "In vitro biocompatibility and antimicrobial activity of chitin monomer obtain from hollow fiber membrane" Designed Monomers and Polymers, Vol. 19, NO. 5, 445–455 (2016) (I. F. = 1.43) |
A. P. Tiwari, S. S. Rohiwal, S. J. Ghosh and S. H. Pawar, "Detection of the pathogenic α-proteobacterium Ochrobactrum anthropi via magnetic enrichment and in-situ PCR using pH responsive BSA@Fe3O4 nanoparticles prior to electrophoretic separation" Microchimica Acta, (DOI 10.1007/s00604-015-1710-6) (I. F. = 3.741) |
|
2015 | R. K. Satvekar, A. P. Tiwari, S. S. Rohiwal, B. M. Tiwale and S. H. Pawar, "A DNA Assembled Fe3O4@Ag Nanorod In Silica Matrix For Cholesterol Biosensing", Journal of Materials Engineering and Performance, doi: 10.1007/s11665-015-1532-z, (2015). (I. F. = 0.998) |
R. K. Satvekar, S. S. Rohiwal, A. P. Tiwari, A. V. Raut, B. M. Tiwale and S. H. Pawar, "Sol Gel Derived Silica/Chitosan/Fe3O4 Nanocomposite For Direct Electrochemistry and Hydrogen Peroxide Biosensing", Materials Research Express,2, (2015), 015402. | |
A. P. Tiwari, R. K. Satvekar, S. S. Rohiwal, P. Ghutepatil, A. V. Raut, V. A. Karande, P. Shete, S. J Ghosh and S. H. Pawar, "Magneto-Separation of Genomic Deoxyribose Nucleic Acid Using pH Responsive Fe3O4@Silica@Chitosan Nanoparticles In Biological Samples", RSC Advances, 5, (2015), 8463. (I. F. = 3.708) |
|
S. S. Rohiwal, R. K. Satvekar, A. P. Tiwari, A. V. Raut, S. G. Kumbhar and S. H. Pawar, "Investigating The Influence of Effective Parameters on Molecular Characteristics of Bovine Serum Albumin Nanoparticles", Applied Surface Science, 334, (2015), 157–164. (I. F. = 2.711) |
|
S. S. Rohiwal, A. P. Tiwari , G. Verma and S. H. Pawar, "Preparation and Evaluation of Bovine Serum Albumin Nanoparticles For Ex Vivo Colloidal Stability In Biological Media", Colloids and Surfaces A: Physicochemical And Engineering Aspects, 480, (2015), 28–37. (I. F. = 2.752) |
|
2014 | R. K. Satvekar, S. S. Rohiwal, A. V. Raut, V. A. Karande, B. M. Tiwale and S. H. Pawar, "A Silica-Dextran Nanocomposite As A Novel Matrix For Immobilization of Horseradish Peroxidase, and Its Application To Sensing Hydrogen Peroxide", Microchimica Acta, 181, 1-2, (2014), 71-77. (I. F. = 3.741) |
Review article
2014 | S. S. Rohiwal and S. H. Pawar, Developments of Biopolymers and Bioconjugate As Wound Healing Materials. M. J. D. Y. P. U. VII, II, (2014), 5-22. ISSN0974-2743. |
Papers abstracted/presented at conferences
2015 | S. S. Rohiwal "Investigation of Zinc Oxide Nanoparticles Incorpoarated Bovine Serum Albumin Nanoparticles as a Potential Facet of Nanomaterial for Antimicrobial Action" Convergence of Stem cells and Medical Nanotechnology (CSCN-2015), D. Y. Patil University, Kolhapur, 2 nd-3 rd September, 2015. |
2014 | S. S. Rohiwal, S. H. Pawar "Preparation and Evaluation of Bovine Serum Albumin Nanoparticles for Ex Vivo Colloidal Stability in Biological Media" National Conference on Recent Trends in Interdisciplinary Research in Material Science 2014 (NCRTIRMS-2014), Department Basic Sciences, Annasaheb Dange College of Engineering & Technology, Ashta, Sangali, 26 th -27 th December, 2014. |
S. S. Rohiwal, S. H. Pawar, "Synthesis and Characterization of Bovine Serum Albumin Nanoparticles As A Drug Vehicle" National Symposium on Current Trends in Chemical and Nanosciences (CTCNS-2014), Department of Chemistry, Shivaji University, Kolhapur, 17th -18th January, 2014. | |
2013 | S. S. Rohiwal, R. K. Satvekar, A. V. Raut, S. H. Pawar "A Green Synthesis of Bovine Serum Albumin-Dextran Conjugates Prepared Through Maillard Reaction" Materials Research Society of India-Annual General Meeting 2011 (MRSI-AGM 2013), IGCAR, Kalpakkam, 11th-13th February, 2013. |
A. V. Raut, R. K. Satvekar, S. S. Rohiwal, "Preparation of Chitosan Oligosaccharides a useful Organic Biomaterial for Medical Technology" Materials Research Society of India-Annual General Meeting 2011 (MRSI-AGM 2013), IGCAR, Kalpakkam, 11th-13th February, 2013. | |
R. K. Satvekar, S. S. Rohiwal, A. V. Raut, "Silica-Chitosan Nanocomposite for Third Generation Hydrogen Peroxide Biosensor" Materials Research Society of India-Annual General Meeting 2011 (MRSI-AGM 2013), IGCAR, Kalpakkam, 11th-13th February, 2013. | |
2012 | S. S. Rohiwal, "Synthesis and Characterization of BSA-Dextran Conjugates" National workshop on Ph.D. Program for Medical Innovations (PPMI-2012), D. Y. Patil University, Kolhapur, 18 th -19 th October, 2012. |
2010 | S. S. Rohiwal, M. V. Padul "Isolation And Analysis Of Cereal, Tuber And Plant Starch" National Conference on Biostatistics and Its Application in Research 2010 at Jijamata college of science and arts Bhenda, Newasa, Ahmednagar, 2010. |
Experimental knowledge
- I had an expertise in the synthesis of natural polymer conjugates, organic nanoparticles, drug encapsulation. I have used different methods for preparation viz; Maillard reaction for the synthesis of polymeric conjugates as well as desolvation for synthesis of organic nanoparticles.
- I had also studied colloidal behaviour of these nanoparticles and polymeric conjugates in different biological media by several spectroscopic and microscopic techniques. To determine the structural and molecular behaviour of synthesized nanoparticles and polymeric conjugates.
- Characterization instruments handled: X-ray diffractometer, PSS-Zeta potential and particle size analyzer, Scanning/Transmission electron microscope (SEM/TEM), Fourier transform infrared (FTIR), Fluorescence spectroscopy, UV-Vis spectrophotometer, Electrochemical work station, FT-Raman spectrometer, Atomic force microscopy, Circular dichroism, Electrophoresis, etc.
- Other techniques known: High resolution transmission electron microscopy (HR-TEM), Field emission scanning electron microscopy (FE-SEM), MALDI-TOF.
- I had also expertise in animal cell culture technique and handled various cell lines.
Conferences/Workshops/ Seminars
2015 | Convergence of Stem cells and Medical Nanotechnology (CSCN-2015), at D. Y. Patil University, Kolhapur. |
2014 | International Workshop on Ph. D. Program for Medical Innovations (IWPPMI-2014), at D. Y. Patil University, Kolhapur. |
National Conference on Recent Trends in Interdisciplinary Research in Material Science 2014 (NCRTIRMS-2014), at Department Basic Sciences, Annasaheb Dange College of Engineering & Technology, Ashta, Sangali. | |
National Symposium on Current Trends in Chemical and Nanosciences (CTCNS-2014), at Department of Chemistry, Shivaji University, Kolhapur. | |
State Level Seminar on Advance in Seperation Technology (2014), at Department of Chemistry, Shree Dhokeshwar College, Takali Dhokeshkar, Parner, Ahmednagar. | |
2013 | Materials Research Society of India-Annual General Meeting (MRSI-AGM 2013), at IGCAR, Kalpakkam. |
2012 | National work shop on Global Trends in Medical Education and Technology (GLOBMET-2012), at D. Y. Patil University, Kolhapur. |
National workshop on "Ph. D. program for medical innovations" (PPMI-2012), at D. Y. Patil University, Kolhapur, Maharashtra. | |
2011 | National conference on Nuclear Energy and Health Care Applications (NEHCA-2011), at D. Y. Patil University, Kolhapur, Maharashtra. |
2010 | National Conference on "Biostatistics and its Application in Research (2010)", at Jijamata college of science and arts Bhenda, Newasa, Ahmednagar, Maharashtra. |