Academic background
| 1977-1980 | Faculty of Sciences, Louis Pasteur University (Strasbourg, France) Biochemistry Ph.D. PhD thesis: Characterization of collagen types and immunolocalization of collagens, laminin and fibronectin in the developing tooth germ |
| 1982-1983 | Max-Planck Institute for Biochemistry (Martinsried, Germany) Biochemistry Postdoc |
| 2004-now | Faculty of Stomatology, Capital University of Medical Sciences (Beijing, China) Dentistry Honorary Professor |
Work experiences
| 1981-1982 | CR2 CNRS, Institute of Medical Biology, Faculty of Medicine (Strasbourg, France) Research scientist |
| 1982-1990 | CR1 CNRS, Institute of Medical Biology, Faculty of Medicine (Strasbourg, France) Research scientist |
| 1990-now | DR2 CNRS, Institute of Medical Biology, Faculty of Medicine (Strasbourg, France) Director of research |
| 1995-2008 | INSERM research unit U424/595 (Strasbourg, France) Team coordinator |
| 2009-2012 | “Tooth Development and Engineering” in the INSERM research unit U977 (Strasbourg, France) Group leader |
| 2013-2015 | “Tooth Development and Engineering” in the INSERM research unit 1109 (Strasbourg, France) Group leader |
| 2016-now | Institute of Animal Physiology and Genetics, The Czech Academy of Sciences Team member |
Research and scientific activities
- Cellular aspects of tooth development and engineering
Scientific evaluations
| 1998-2015 | Member of the Editorial board of the Journal of Dental Research |
| 2010-2016 | Associate Editor for Frontiers of Craniofacial Biology |
| 2011-now | Member of the Editorial board of the International Journal of Developmental Biology |
| 1992-2015 | Referee for selected journals: Development, Developmental Biology, Archives of Oral Biology, European Journal of Oral Science, Journal of Molecular Histology, Connective Tissue Research, etc. |
| 1993-2015 | Evaluations of applications for public research organizations in France, Europe, Israel, Japan and USA. |
Member of scientific organisations
| 1995-2003 | The European Cost Action B8 “Odontogenesis” |
| 2003-2008 | Research Academic Frontier Project H15 on Tooth Morphogenesis (supported by the Japanese ESSCT Ministery) |
| 2004-2008 | Management Committee of the European COST B23 Action “Oral Facial Development and Regeneration” (representant for France) |
| 2008-2012 | Research network „Tooth Morphogenesis and Engineering“ (supported by the Japanese ESSCT Ministery) |
Member of the scientific board of conferences, workshops, symposiums
| 2001 | 7th Int. Conference on the Chemistry and Biology of Mineralized Tissue, Ponte-Vedra, USA |
| 2001 | 8th Int. Conference on Tooth Morphogenesis and Differentiation, La Londe-les-Maures, France |
| 2003 | Tooth and Orofacial Development: From Bench to Clinic, Prague, Czech Republic |
| 2004 | 8th Int. Tooth Morphogenesis and Development Meeting, York, UK |
| 2004 | 8th Int. Conference on the Chemistry and Biology of Mineralized Tissue, Banff, Canada |
| 2005 | 13th Int. Symposium on Dental Morphology, Lodz, Poland |
| 2007 | 9th Int. Conference on Tooth Morphogenesis and Differentiation, Zurich, Switzerland |
| 2008 | 2nd Int. Workshop on Biomaterial Sciences, Sucevita, Romania |
| 2010 | 10th Int. Conference on Tooth Morphogenesis and Differentiation, Berlin, Germany |
| 2011 | 1st Int. Seminary on Biomaterials and Regenerative Medicine, Gura Humorului, Romania |
| 2013 | 11th Int. Conference on Tooth Morphogenesis and Differentiation, La Londe-Les-Maures |
| 2013 | 2nd Int. Seminary on Biomaterials & Regenerative Medicine, Iasi, Romania |
Publications
- Author or coauthor of 151 IF contributions
- cited 5029 times (4096 times without self-citations)
- h-index = 36 (according WOS)
- Co-author of 11 book chapters, and participation to international meetings (144 oral presentations and co-author of 125 poster communications)
Recent publications
| 2017 | Budisova-Svandova E., Vesela B., Lesot H., Poliard A., Matalova E. Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. Histochem. & Cell Biol., 2017 Apr;147(4):497-510. |
| 2016 | Bécavin T., Kuchler-Bopp S., Kökten T, Huck O., Messaddeq N., Lesot H., Deveaux E., Benkirane-Jessel N., Keller L. Well-organized spheroids as a new platform to examine cells interaction and behaviour during organ development. Cell Tissue Res. 2016 Dec;366(3):601-615. |
| Dosedělová H., Štěpánková K., Zikmund T., Lesot H., Kaiser J., Novotný K., Štembírek J, Knotek Z., Zahradníček O, Buchtová M. Age-related changes in tooth-bone interface area of acrodont dentition in the chameleon. J. Anat. 2016, 229(3), 356-368. | |
| Kuchler-Bopp S., Bécavin T., Kökten T., Weickert J.L., Keller L., Lesot H., Deveaux E., Benkirane-Jessel N. Three-dimensional micro-culture system for tooth tissue engineering. J. Dent Res., 2016. 95(6), 657-664 | |
| 2015 | Blackburn J., Kawasaki K., Porntaveetus T., Kawasaki M., Otsuka-Tanaka Y., Miake Y., Ota M.S., Watanabe M., Hishinuma M., Nomoto T., Oommen S., Ghafoor S., Harada F., Nozawa-Inoue K., Maeda T., Peterková R., Lesot H., Inoue J-I., Akiyama T., Schmidt-Ullrich R., Liu B., Hu Y., Page A., Ramírez A., Sharpe P.T., Ohazama A. Excess NF-kB induces ectopic odontogenesis in embryonic incisor epithelium. J. Dent. Res., 2015, 94(1), 121-128. |
| Dosedělová H, Dumková J, Lesot H, Glocová K, Kunová M, Tucker AS, Veselá I, Krejčí P, Tichý F, Hampl A, Buchtová M. Fate of the molar dental lamina in the monophyodont mouse. PLoS One. 2015 May 26;10(5):e0127543. doi: 10.1371/journal.pone.0127543. eCollection 2015. | |
| Keller L., Kökten T., Kuchler-Bopp S., Lesot H. Tooth organ engineering. In “Stem Cell Biology and Tissue Engineering in Dental Sciences.” (A. Vishwakarma, P. Sharpe, S. Shi, X.-P. Wang, M. Ramalingam, Eds). 2015, pp359–368. ISBN: 978-0-12-397157-9. |