Mgr. Rajan Iyyappan, Ph.D.

Education

May 2018-now Post-Doctoral fellow
Laboratory of Biochemistry and Molecular Biology of Germ Cells, IAPG, The Czech Academy of Sciences, Czech Republic
March 2016-July 2017 Post-Doctoral fellow
Department of Biochemistry, Indian Institute of Science, Bangalore, India
March 2009-May 2014 Ph.D. Biotechnology
Department of Biotechnology, University of Calicut, Kerala, India.
Dec 2003-May 2007 M.Sc. Medical Biochemistry
School of Health Sciences, University of Calicut, Kerala, India

Professional experience

July 2015-March 2016 Sri Ramachandra Medical College & Research Institute, Porur, Chennai, India
July 2014-July 2015 Assistant Professor : Pazhassi Raja College, Pulpally, Wayanad, Kerala, India
February 2008-February 2009 Tutor : Pondicherry Institute of Medical Sciences, Puducherry, India

Major scientific interests

  • RNA binding protein and mRNA Translation Regulation
  • Post transcriptional modification
  • Translational regulation in Cell cycle

Important Publications

2018 Bhatter N, Iyyappan R and Rajyaguru PI. Characterizing mutations in and genetic interactions of RGG-motif translation repressor Sbp1. Wellcome Open Res 2018, 3:102
2015 Rajan I, Jayasree PR, Kumar PR. Zerumbone induces mitochondria-mediated apoptosis via increased calcium, generation of reactive oxygen species and upregulation of soluble histone H2AX in K562 chronic myelogenous leukemia cells. Tumor Biol. 2015 Nov;36(11):8479-89
2014 Rajan I, Rabindran R, Nithya N, Lakshmipriya T, Jayasree PR, Kumar PR. Assessment of cell cycle phase-specific effects of zerumbone on mitotically synchronous surface cultures of Physarum polycephalum. Protoplasma. 2014 Jul;251(4):931-41
2013 Rajan I, Narayanan N, Rabindran R, Jayasree PR, Manish Kumar PR. Zingerone protects against stannous chloride-induced and hydrogen peroxide-induced oxidative DNA damage in vitro. Biol Trace Elem Res. 2013 Dec;155(3):455-9.