Employees

Projects

Macholán Miloš, prof., RNDr., CSc.


Function:
Profession:vedoucí
E-mail:
Telephone: +420 532 290 138
Mobile phone:
Department: Laboratory of Mammalian Evolutionary Genetics
Building: Brno/
Institutional service phone:
Web:

Curriculum vitae:

1983 – 1988

Masaryk University (previously J.E. Purkyne University) in Brno, general biology

1988 – 1993

PhD at the Institute of Systematic and Ecological Biology of the Czechoslovak Academy of Sciences

1993 – 2005

researcher, Institute of Animal Physiology and Genetics, AS CR

1997 – 2001

head of Laboratory of Genetics and Embryology, IAPG

2003

Associated Professor, Masaryk University in Brno, Systematic zoology and Ecology

2005 – present

senior researcher and head of the Laboratory of Mammalian Evolutionary Genetics

2008

Professor of Zoology, MU Brno

Specialization:

Genetic and phenetic variation and systematics of small mammals, evolution of the genus Mus, hybridization and speciation in house mice

Awards:

1988

Dean’s Award (Masaryk University)

1997

Kumpošt Award (best article, journal Vesmír)

2002

Otto Wichterle Award for Young Scientists (ASCR)

2007

Purkyně Award (best article, journal Živa)

Societies:

 

Society of Systematic Biologists (member)

 

Society for Molecular Biology and Evolution (member)

 

European Society for Evolutionary Biology (member)

Internship abroad:

1990

IEMEŽ, RAS, Moscow

1992

University of Lausanne, Switzerland

1993

Universita Roma II „Tor Vergata“, Italy

Publications:

2005

Božíková E, Munclinger P, Teeter KC, Tucker PK, Macholán M, Piálek J (2005) Mitochondrial DNA in the hybrid zone between Mus musculus musculus and Mus musculus domesticus: a comparison of two transects. Biol. J. Linn. Soc., 84: 363-378. PDF

 2006

Macholán M (2006) A geometric morphometric analysis of the shape of the first upper molar in mice of the genus Mus (Muridae, Rodentia). J. Zool., 269: 672-681. PDF

2007

Macholán M., Munclinger P., Šugerková M. et al. (2007) Genetic analysis of autosomal and x-linked markers across a mouse hybrid zone. Evolution, 61: 746-771. PDF

 

Macholán M, Vyskočilová M, Bonhomme F, Kryštufek B, Orth A, Vohralík V (2007) Genetic variation and phylogeography of free-living mouse species (genus Mus) in the Balkans and the Middle East. Mol. Ecol., 16: 4774-4788. PDF

2008

Piálek J, Vyskočilová M, Bímová B ... Macholán M et al. (2008) Development of unique house mouse resources suitable for evolutionary studies of speciation. J. Hered., 99: 34-44. PDF

 

Mikula O, Macholán M (2008). There is no heterotic effect upon developmental stability of the ventral side of the skull in the Mus musculus musculus/M. m. domesticus hybrid zone. J. Evol. Biol., 21: 1055–1067. PDF

 

Macholán M, Baird SJE, Munclinger P, Dufková P, Bímová B, Piálek J (2008) Genetic conflict outweighs heterogametic incompatibility in the mouse hybrid zone? BMC Evol. Biol., 8: 271. PDF

2009

Bímová B, Albrecht T, Macholán M, Piálek J (2009) Signalling components of the house mouse mate recognition system. Behav. Process., 80: 20-27. PDF

2010

Mikula, O., Auffray, J.-C., Macholán, M., 2010: Asymmetric size and shape variation in the Central European transect across the house mouse hybrid zone. Biol. J. Linn. Soc., 101: 13-27. PDF

2011

Dufková P, Macholán M, Piálek J (2011) Inference of selection and stochastic effects in the house mouse hybrid zone. Evolution, 65: 993–1010. PDF

 

Macholán M, Baird SJE, Dufková P, Munclinger P, Vošlajerová Bímová B, Piálek J (2011) Assessing multilocus introgression patterns: A case study on the mouse X chromosome in Central Europe. Evolution, 65: 1428-1446. PDF

 

Vošlajerová Bímová B, Macholán M, Baird SJE et al. (2011) Reinforcement selection acting on the European house mouse hybrid zone. Mol. Ecol., 20: 2403-2424. PDF

 

Wang L, Luzynski K, Pool J ... Macholán M et al. (2011) Measures of linkage disequilibrium among neighboring SNPs indicate asymmetries across the house mouse hybrid zone. Mol. Ecol., 20: 2985-3000. PDF

2012

Janoušek, V., Wang, L., Luzynski, K., Dufková, P., Mrkvicová Vyskočilová, M., Nachman, M.W., Munclinger, M., Macholán, M., Piálek, J., Tucker, P.K., 2012: Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus. Mol. Ecol., 21: 3032-3047. PDF

 

Baird, S.J.E., Macholán, M., 2012: What can the Mus musculus musculus/M. m. domesticus hybrid zone tell us about speciation? In Macholán, M., Baird, S.J.E., Munclinger, P., Piálek, J. (eds.): Evolution of The House Mouse. Cambridge Studies in Morphology and Molecules: New Paradigms in Evolutionary Biology. Cambridge University Press, Cambridge, pp. 334-372. PDF

 
Baird, S.J.E., Ribas, A., Macholán, M., Albrecht, T., Piálek, J., Goüy de Bellocq, J., 2012: Where are the wormy mice? A re-examination of hybrid parasitism in the European house mouse hybrid zone. Evolution, 66(9): 2757-2772. PDF
 

Albrechtová, J. ; Albrecht, T. ; Baird, S. J. E. ; Macholán, M. ; Rudolfsen, G. ; Munclinger, P. ; Tucker, P. K. ; Piálek, J., 2012: Sperm-related phenotypes implicated in both maintenance and breakdown of a natural species barrier in the house mouse. Proceedings of the Royal Society of London. B - Biological Sciences, 279(1748): 4803-4810. PDF

 

Ďureje, Ľ., Macholán, M., Baird, S.J.E., Piálek, J., 2012: The mouse hybrid zone in Central Europe: from morphology to molecules. Folia Zool., 61(3-4), 308-318. PDF

 

Hiadlovská, Z., Strnadová, M., Macholán, M., Vošlajerová Bímová, B., 2012: Is water really a barrier for the house mouse? A comparative study of two mouse subspecies. Folia Zool., 61(3-4), 319-329. PDF

 

Macholán, M., Mrkvicová Vyskočilová, M., Bejček, V., Šťastný, K., 2012: Mitochondrial DNA sequence variation and evolution of Old World house mice (Mus musculus). Folia Zool., 61(3-4), 284-307. PDF

2013

Hiadlovská, Z., Vošlajerová Bímová, B., Mikula, O., Piálek, J., Macholán, M., 2013: Transgressive segregation in a behavioural trait? Explorative strategies in two house mouse subspecies and their hybrids. Biol. J. Linn. Soc., 108(1): 225-235. PDF

 

Zima, J., Arslan, A., Benda, P., Macholán, M., Kryštufek, B., 2013: Chromosomal variation in social voles: a Robertsonian fusion in the Guenther's vole. Acta Theriol., 58(3): 255-265. PDF

 

Kváč, M., McEvoy, J., Loudová, M., Stenger, B., Sak, B., Květoňová, D., Ditrich, O., Rašková, V., Moriarty, E., Rost, M., Macholán, M., Piálek, J., 2013: Coevolution of Cryptosporidium tyzzeri and the house mouse (Mus musculus). Int. J. Parasitol., 43: 805-817. PDF

2014

Fornuskova, A., Bryja, J., Vinkler, M., Macholán, M.,Piálek, J. 2014: Contrasting patterns of polymorphism and selection in bacterial-sensing toll-like receptor 4 in two house mouse subspecies. Ecol. Evol. 4: 2931-2944. PDF

  Hiadlovská, Z., Macholán, M., Mikula, O., Vošlajerová Bímová, B. 2014: The meek inherit the earth: less aggressive wild mice are more successful in challenging situations. Biol. J. Linn. Soc. 113: 310-319. PDF

 

 

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