Certified methods

 

Methodology of Generation of Acute and Transgenic model of Huntington's disease in miniature pig and its application for testing of new drugs and therapeutic approaches for neurodegenerative diseases

The methodology describes generation of biomedical model of Huntington's disease in miniature pig. The model was generated for preclinical testing of new potential treatments which are developed with using of both pharmacological and molecular biological methods.

Authors: Jan Motlik, Stefan Juhas, Jana Juhasova, Petr Vodicka, Monika Baxa

 

Methodology of Generation of a Model of Traumatic Spinal Cord Injury in miniature pig and its application for testing of new therapies and drugs

The methodology describes the possibility of using of reproducible and adjustable model of spinal cord injury in miniature pig. The model was generated for testing of new drugs and therapeutic approaches which are potentially useful in the treatment of acute or chronic spinal cord injury in human patients.

Authors: Martin Marsala, Jan Motlik, Stefan Juhas, Jana Juhasova