prof. RNDr. Miloš Macholán, CSc.

Curriculum vitae

2008-now Professor of Zoology, MU Brno
2005-now senior researcher and head of the Laboratory of Mammalian Evolutionary Genetics
2003 Associated Professor, Masaryk University in Brno, Systematic zoology and Ecology
1997-2001 head of Laboratory of Genetics and Embryology, IAPG CAS
1993-2005 researcher, Institute of Animal Physiology and Genetics, CAS
1988-1993 Ph.D. at the Institute of Systematic and Ecological Biology of the Czechoslovak Academy of Sciences
1983-1988 Masaryk University (previously J.E. Purkyne University) in Brno, general biology


Major scientific interests

  • Genetic and phenetic variation and systematics of small mammals
  • evolution of the genus Mus
  • hybridization and speciation in house mice


Fellowships, prizes

2007 Purkyně Award (best article, journal Živa)
2002 Otto Wichterle Award for Young Scientists (CAS)
1997 Kumpošt Award (best article, journal Vesmír)
1988 Dean’s Award (Masaryk University)


Membership in academic councils and editorial boards

  • Society of Systematic Biologists (member)
  • Society for Molecular Biology and Evolution (member)
  • European Society for Evolutionary Biology (member)


Research fellowships and study visits

1993 Universita Roma II „Tor Vergata“, Italy
1992 University of Lausanne, Switzerland
1990 IEMEŽ, RAS, Moscow



2014 Hiadlovská, Z., Macholán, M., Mikula, O., Vošlajerová Bímová, B. 2014: The meek inherit the earth: less aggressive wild mice are more successful in challenging situations. Biol. J. Linn. Soc. 113: 310-319. PDF
  Fornuskova, A., Bryja, J., Vinkler, M., Macholán, M.,Piálek, J. 2014: Contrasting patterns of polymorphism and selection in bacterial-sensing toll-like receptor 4 in two house mouse subspecies. Ecol. Evol. 4: 2931-2944. PDF
2013 Kváč, M., McEvoy, J., Loudová, M., Stenger, B., Sak, B., Květoňová, D., Ditrich, O., Rašková, V., Moriarty, E., Rost, M., Macholán, M., Piálek, J., 2013: Coevolution of Cryptosporidium tyzzeri and the house mouse ( Mus musculus ). Int. J. Parasitol., 43: 805-817. PDF
  Zima, J., Arslan, A., Benda, P., Macholán, M., Kryštufek, B., 2013: Chromosomal variation in social voles: a Robertsonian fusion in the Guenther's vole. Acta Theriol., 58(3): 255-265. PDF
  Hiadlovská, Z., Vošlajerová Bímová, B., Mikula, O., Piálek, J., Macholán, M., 2013: Transgressive segregation in a behavioural trait? Explorative strategies in two house mouse subspecies and their hybrids. Biol. J. Linn. Soc., 108(1): 225-235. PDF
2012 Macholán, M., Mrkvicová Vyskočilová, M., Bejček, V., Šťastný, K., 2012: Mitochondrial DNA sequence variation and evolution of Old World house mice ( Mus musculus ). Folia Zool., 61(3-4), 284-307. PDF
  Hiadlovská, Z., Strnadová, M., Macholán, M., Vošlajerová Bímová, B., 2012: Is water really a barrier for the house mouse? A comparative study of two mouse subspecies. Folia Zool., 61(3-4), 319-329. PDF
  Ďureje, Ľ., Macholán, M., Baird, S.J.E., Piálek, J., 2012: The mouse hybrid zone in Central Europe: from morphology to molecules. Folia Zool., 61(3-4), 308-318. PDF
  Albrechtová, J. ; Albrecht, T. ; Baird, S. J. E. ; Macholán, M. ; Rudolfsen, G. ; Munclinger, P. ; Tucker, P. K. ; Piálek, J., 2012: Sperm-related phenotypes implicated in both maintenance and breakdown of a natural species barrier in the house mouse. Proceedings of the Royal Society of London. B - Biological Sciences, 279(1748): 4803-4810. PDF
  Baird, S.J.E., Ribas, A., Macholán, M., Albrecht, T., Piálek, J., Goüy de Bellocq, J., 2012: Where are the wormy mice? A re-examination of hybrid parasitism in the European house mouse hybrid zone. Evolution, 66(9): 2757-2772. PDF
  Baird, S.J.E., Macholán, M., 2012: What can the Mus musculus musculus/M. m. domesticus hybrid zone tell us about speciation? In Macholán, M., Baird, S.J.E., Munclinger, P., Piálek, J. (eds.): Evolution of The House Mouse. Cambridge Studies in Morphology and Molecules: New Paradigms in Evolutionary Biology. Cambridge University Press, Cambridge, pp. 334-372. PDF
  Janoušek, V., Wang, L., Luzynski, K., Dufková, P., Mrkvicová Vyskočilová, M., Nachman, M.W., Munclinger, M., Macholán, M., Piálek, J., Tucker, P.K., 2012: Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus . Mol. Ecol., 21: 3032-3047. PDF
2011 Wang L, Luzynski K, Pool J ... Macholán M et al. (2011) Measures of linkage disequilibrium among neighboring SNPs indicate asymmetries across the house mouse hybrid zone. Mol. Ecol., 20: 2985-3000. PDF
  Vošlajerová Bímová B, Macholán M, Baird SJE et al. (2011) Reinforcement selection acting on the European house mouse hybrid zone. Mol. Ecol., 20: 2403-2424. PDF
  Macholán M, Baird SJE, Dufková P, Munclinger P, Vošlajerová Bímová B, Piálek J (2011) Assessing multilocus introgression patterns: A case study on the mouse X chromosome in Central Europe. Evolution, 65: 1428-1446. PDF
  Dufková P, Macholán M, Piálek J (2011) Inference of selection and stochastic effects in the house mouse hybrid zone. Evolution, 65: 993–1010. PDF
2010 Mikula, O., Auffray, J.-C., Macholán, M., 2010: Asymmetric size and shape variation in the Central European transect across the house mouse hybrid zone. Biol. J. Linn. Soc., 101: 13-27. PDF
2009 Bímová B, Albrecht T, Macholán M, Piálek J (2009) Signalling components of the house mouse mate recognition system. Behav. Process., 80: 20-27. PDF
2008 Macholán M, Baird SJE, Munclinger P, Dufková P, Bímová B, Piálek J (2008) Genetic conflict outweighs heterogametic incompatibility in the mouse hybrid zone? BMC Evol. Biol., 8: 271. PDF
  Mikula O, Macholán M (2008). There is no heterotic effect upon developmental stability of the ventral side of the skull in the Mus musculus musculus/M. m. domesticus hybrid zone. J. Evol. Biol., 21: 1055–1067. PDF
  Piálek J, Vyskočilová M, Bímová B ... Macholán M et al. (2008) Development of unique house mouse resources suitable for evolutionary studies of speciation. J. Hered., 99: 34-44. PDF
2007 Macholán M, Vyskočilová M, Bonhomme F, Kryštufek B, Orth A, Vohralík V (2007) Genetic variation and phylogeography of free-living mouse species (genus Mus ) in the Balkans and the Middle East. Mol. Ecol., 16: 4774-4788. PDF
  Macholán M., Munclinger P., Šugerková M. et al. (2007) Genetic analysis of autosomal and x-linked markers across a mouse hybrid zone. Evolution, 61: 746-771. PDF
2006 Macholán M (2006) A geometric morphometric analysis of the shape of the first upper molar in mice of the genus Mus (Muridae, Rodentia). J. Zool., 269: 672-681. PDF
2005 Božíková E, Munclinger P, Teeter KC, Tucker PK, Macholán M, Piálek J (2005) Mitochondrial DNA in the hybrid zone between Mus musculus musculus and Mus musculus domesticus : a comparison of two transects. Biol. J. Linn. Soc., 84: 363-378. PDF